Surfactant Function in Neonates with Respiratory Distress Syndrome
نویسندگان
چکیده
منابع مشابه
Surfactant function in neonates with respiratory distress syndrome.
The function of pulmonary surfactant of a group of 14 preterm neonates (birth weight 907 +/- 60 g) who suffered from severe respiratory distress syndrome (RDS) and who had received exogenous bovine lipid extracted surfactant on the first day of life was compared to that in a second group of 8 neonates (birth weight 940 +/- 110 g) with mild RDS who had not received surfactant treatment. Mechanic...
متن کاملSurfactant Function in Adult Respiratory Distress Syndrome*
W e have reported previously on abnormalities of human surf actant in a lung from a patient with the adult respiratory distress syndrome (ARDS) following trauma and shock.’ The lung with ARDS was compared to three normal lungs obtained from transplant donors. An abnormal static pressure-volume curve indicated reduced compliance and abnormally high surfactant film compressibility was found, but ...
متن کاملSurfactant Replacement Therapy Beyond Respiratory Distress Syndrome in Neonates.
BACKGROUND Surfactant replacement therapy is an established modality of treatment in preterm neonates with respiratory distress syndrome. In addition, there are various neonatal respiratory disorders which are characterized by surfactant deficiency in which surfactant therapy can be a feasible and safe option. OBJECTIVE To collate the literature on the use of surfactant replacement therapy in...
متن کاملSurfactant protein b expression in bronchoalveolar lavage fluid of full-term neonates with respiratory distress syndrome.
The aim was to investigate the surfactant protein B (SP-B) expression in the bronchoalveolar lavage fluid (BALF) of full-term neonates with respiratory distress syndrome (RDS). The enzyme-linked immunosorbent assay was performed to assess SP-B expression in BALF of 60 full-term neonates with RDS and 23 healthy neonates and correlation of SP-B level with RDS classification according to chest x-r...
متن کاملNatural surfactant substitution in respiratory distress syndrome.
Natural surfactants consist of unique proteins and lipids. Their effectiveness in improving subnormal lung function in surfactant deficiency should be established prior to any clinical trials. Rigorous tests are required to document batch to batch variability in surface activity and to exclude toxic contaminants. Up to this date randomized clinical trials in small preterm infants have demonstra...
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ژورنال
عنوان ژورنال: Respiration
سال: 1998
ISSN: 0025-7931,1423-0356
DOI: 10.1159/000029245